AmericanPeptide
Design LabBeta

Beta · in development. A research-use sequence property calculator. Property values are estimates — cross-check before relying on them. Prefer a hands-on, gamified build? Try PeptideForge.

Peptide Design Lab

Build a sequence, paste one, or load a catalog peptide — then read molecular weight, pH-dependent net charge, isoelectric point, GRAVY, and the 280 nm extinction coefficient in real time.

Sequence

Load from catalog:
Nonpolar
Polar
Acidic (−)
Basic (+)

pH environment

pH 7.4
0 · acidic7.4 · physiological14 · basic

Length

15

residues

Molecular weight

1,419.55

Da (avg)

Net charge @ pH 7.4

-2

e

Isoelectric point

3.55

pI

GRAVY

-0.69

hydropathy

Extinction ε₂₈₀

0

M⁻¹·cm⁻¹ (reduced)

A280 (0.1%)

0

1 g/L

Aromatic

0

F/W/Y/H

Cysteines

0

thiols

Composition

Nonpolar: 11Polar: 0Acidic (−): 3Basic (+): 1

Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Synthesis difficulty

moderate
  • Moderate length. 15 residues — more coupling cycles than a short peptide; per-cycle losses compound.
  • Proline-rich. High proline content can slow couplings and complicate folding.
  • Repeat run. Three or more identical residues in a row can be harder to couple cleanly.

Heuristic estimate from sequence — see the synthesis guide for what drives cost & purity.

AI design analysis

Get a research-framed read on this sequence — charge & solubility, stability & synthesis liabilities, and similar known peptides. Not medical, dosing, or administration advice.

3D structure

Predict a 3D structure for this sequence.

Structure predicted with ESMFold (Meta) — a computational prediction, not an experimental structure. For larger or higher-confidence models, use AlphaFold Server below.

From design to bench

  1. Define goal
  2. Predict propertiesyou are here
  3. 3D structure
  4. Optimize sequence
  5. Validate folding
  6. Lab synthesis

External research tools open in a new tab. AmericanPeptide is not affiliated with and does not endorse these services.

Research use only. Computed properties are estimates for educational/research reference, not medical advice or an offer for sale. Validate independently.