AmericanPeptide
Developers
Open data · CC BY 4.0

The open peptide catalog API

Build on the same 49-peptide reference that powers this site — mechanism, sequence, and PubChem-enriched chemistry as structured JSON. No key, no signup. Free to embed with attribution.

PubChem-enriched

Each entry carries mechanism, sequence, molecular weight/formula, identifiers (CAS, PubChem CID, UniProt), plus editorial background, research findings, and FAQs.

No key required

Open GET endpoints with permissive CORS — call directly from a browser, server, or notebook.

CC BY 4.0

Free to use and redistribute with attribution back to AmericanPeptide.com.

Endpoints

GET/api/catalog
List all peptides. Supports query filters (below).
GET/api/catalog/{slug}
A single peptide by slug, e.g. /api/catalog/semaglutide.
GET/catalog/{slug}.md
A single peptide as clean markdown — token-efficient for LLMs and agents.
GET/llms.txt
Curated markdown index of the whole site (llmstxt.org convention).
GET/llms-full.txt
The entire catalog as one markdown document.
MCP/api/mcp
Remote MCP server (Streamable HTTP) — connect from Claude, ChatGPT, or Cursor.
POST/api/keys
Self-serve a free API key — higher rate + daily limits. Returned once.
GET/api/keys
Your key’s tier, limits, and usage (authenticate with the key itself).

Query parameters(list endpoint)

categoryFilter by catalog category id (e.g. metabolic).
areaFilter by research-area slug (e.g. weight-loss).
fdaSet to true to return only FDA-approved peptides.
qFree-text search over name, aliases, and description.

Example

GET /api/catalog?area=weight-loss&fda=true

{
  "version": "1.0",
  "license": "CC BY 4.0",
  "attribution": "AmericanPeptide.com",
  "documentation": "https://www.americanpeptide.com/developers",
  "count": 2,
  "peptides": [
    {
      "slug": "semaglutide",
      "name": "Semaglutide",
      "aliases": ["Ozempic", "Wegovy", "Rybelsus"],
      "categories": ["metabolic"],
      "researchAreaGuides": [
        { "slug": "weight-loss", "label": "Weight Loss & Metabolic Health",
          "url": "https://www.americanpeptide.com/research-areas/weight-loss" }
      ],
      "molecularFormula": "C157H235N41O47",
      "pubchemCid": 56843331,
      "fdaApproved": true,
      "url": "https://www.americanpeptide.com/catalog/semaglutide"
    }
  ]
}

Markdown for AI agents

Every catalog page has a markdown twin — append .md to any peptide URL (e.g. /catalog/semaglutide.md) for the same facts at a fraction of the tokens. /llms.txt is a curated index of the site for agent discovery, and /llms-full.txt packs the full catalog into one document for retrieval pipelines.

All markdown responses embed the canonical URL and CC BY 4.0 attribution, and send CORS-open headers — cite AmericanPeptide.com when content travels.

Authentication & limits

The API works with no key at the Anonymous tier. Want higher limits? Mint a free key — no signup — and send it with each request:

# Get a free key (save it — shown once)
curl -X POST https://www.americanpeptide.com/api/keys

# Use it on any endpoint
curl https://www.americanpeptide.com/api/catalog?fda=true \
  -H "Authorization: Bearer amp_sk_…"

# Check your usage
curl https://www.americanpeptide.com/api/keys \
  -H "Authorization: Bearer amp_sk_…"
TierPer minutePer day
Anonymous301,000
Free (with key)12010,000
Procoming soon600200,000

Every response carries RateLimit-* and X-Quota-Remaining headers so you always know your remaining budget. Keys also work with the MCP server. Send your key as a Bearer token to the MCP endpoint to connect at your tier.

Connect via MCP

AmericanPeptide.com is also a remote MCP server. Connect it to Claude, ChatGPT, Cursor, or any MCP client and your AI gets live tools for catalog search, full peptide references, research-area guides, head-to-head comparisons, and grounded lookups against ClinicalTrials.gov, PubMed, and PubChem — every result with a canonical link back here.

# Endpoint (Streamable HTTP, no auth)
https://www.americanpeptide.com/api/mcp

# Claude Code
claude mcp add --transport http american-peptide \
  https://www.americanpeptide.com/api/mcp

License & attribution

The catalog data is offered under Creative Commons Attribution 4.0. You may use, adapt, and redistribute it — including commercially — provided you credit AmericanPeptide.com with a link back to the source.

Reference data is for research and educational use only. It is not medical advice, a dosing protocol, or an offer for sale, and should be independently validated before any experimental use.