5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT). Preclinical work links NNMT inhibition to improvements in adipose tissue metabolism and skeletal muscle aging.
5-Amino-1MQ is a small molecule — not a peptide — that is frequently catalogued alongside research peptides because of its metabolic focus. It selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT).
NNMT consumes methyl groups and influences cellular NAD+ and SAM pools; inhibiting it is studied in preclinical work for improved adipose-tissue metabolism and muscle aging. It is a research compound and is not FDA-approved.
NNMT inhibition → preserved cellular NAD+ / SAM pools.
Behind every vial of 5-Amino-1MQ is the same exacting pipeline every research peptide runs — but the chemistry plays out differently for this molecule. Here is how 5-Amino-1MQ, specifically, is brought into being.
On paper, 5-Amino-1MQ is C10H11N2+ — about 159.21 daltons of precisely arranged atoms. Before a single bond is made, the target sequence, salt form, and purity threshold are written down as the contract the finished material must meet.
5-Amino-1MQ is assembled by solid-phase peptide synthesis — the chain grows one protected residue at a time on resin, and what you fail to build cleanly here you pay to remove later.
The crude mixture — 5-Amino-1MQ plus its deletions and side products — is then separated on preparative HPLC, and where the cut is taken decides the difference between a genuinely pure peptide and a barely-passable one.
A real batch of 5-Amino-1MQ proves itself: identity confirmed by mass spectrometry against its ~159.21 Da, purity read directly off an analytical HPLC trace, water and counterion content measured. That batch-specific certificate of analysis is the only honest way to know what is actually in a vial of 5-Amino-1MQ — and a short, cold, accountable chain of custody is how that purity survives the trip to your bench.
Producing 5-Amino-1MQ to a genuine purity spec means solid-phase synthesis, preparative HPLC purification, and batch quality control — none of it cheap, and none of it something you can verify by eye.
Don't judge a vial by its cake. A fluffy, good-looking lyophilized powder reflects bulking agents and freeze-drying parameters — not purity. Insist on a batch-specific certificate of analysis.
5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT, studied in metabolic and aging research; it is catalogued here alongside peptides for its metabolic relevance.
No — it is a small molecule, not a peptide, but it is grouped with metabolic research compounds.
Obesity, sarcopenia (muscle aging), and NAD+ biology, primarily in preclinical models.
No — it is a research compound. This page is a research and educational reference.
Dosing protocols, mechanism, comparisons, and the latest trials — citation-backed answers grounded in PubMed, PubChem, and ClinicalTrials.gov.